BDBM50466161 CHEMBL4281037

SMILES Nc1cncc(c1)-c1cc(cs1)-c1cccnc1

InChI Key InChIKey=SHHUBFYLSRKFFE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50466161   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50466161(CHEMBL4281037)
Affinity DataIC50: 101nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21(DE3) using KKISGRLSPIMTEQ-NH2 as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50466161(CHEMBL4281037)
Affinity DataIC50: 101nMAssay Description:Inhibition of recombinant full length human Dyrk1A expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50466161(CHEMBL4281037)
Affinity DataIC50: 154nMAssay Description:Inhibition of recombinant full length human Dyrk1B expressed in Baculovirus expression system using KKISGRLSPIMTEQ as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed