BDBM50466314 CHEMBL4280705

SMILES [H][C@]12O[C@H](OCCN3CCN(CC3)c3ccc(C(=O)NS(=O)(=O)c4ccc(NCC5CCOCC5)c(c4)[N+]([O-])=O)c(Oc4cnc5[nH]ccc5c4)c3)[C@](C)(O)[C@]3([H])CC[C@@H](C)[C@]4([H])CC[C@@](C)(OO[C@@]134)O2

InChI Key InChIKey=XPBOFBDQTPKWTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466314   

TargetApoptosis regulator Bcl-2(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466314(CHEMBL4280705)
Affinity DataIC50: 87nMAssay Description:Inhibition of FAM-labelled Bax binding to Bcl2 (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50466314(CHEMBL4280705)
Affinity DataIC50: 287nMAssay Description:Inhibition of FAM-labelled Bax binding to Bcl-xL (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed