BDBM50466370 CHEMBL4285485

SMILES CCOC(=O)C(C)(C)c1ccc(NC(=O)Cc2ccc(cc2)S(=O)(=O)CC)cc1

InChI Key InChIKey=FHABWAHHBSKNOS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50466370   

TargetNuclear receptor ROR-gamma(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466370(CHEMBL4285485)
Affinity DataIC50: 64nMAssay Description:Displacement of [3H]-Digoxin from recombinant human GST-fused RORgammat LBD after 1 to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466370(CHEMBL4285485)
Affinity DataIC50: 400nMAssay Description:Transrepression of recombinant human GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466370(CHEMBL4285485)
Affinity DataIC50: 3.10E+3nMAssay Description:Transrepression of recombinant mouse GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed