BDBM50466386 CHEMBL4286603

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)C(C)(C)C(=O)Nc2cc(Cl)ccn2)cc1

InChI Key InChIKey=RRFLKMHAGGWGSE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466386   

TargetNuclear receptor ROR-gamma(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466386(CHEMBL4286603)
Affinity DataIC50: 8.20nMAssay Description:Transrepression of recombinant human GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466386(CHEMBL4286603)
Affinity DataIC50: 100nMAssay Description:Transrepression of recombinant mouse GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed