BDBM50466392 CHEMBL4285448

SMILES CC(C)c1nc2c(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)ccnc2[nH]1

InChI Key InChIKey=GZECANYKHKCEFF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50466392   

TargetTyrosine-protein kinase receptor TYRO3(Human)
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466392(CHEMBL4285448)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant GST-tagged human Tyro3 (451 to 890 residues) cytoplasmic domain expressed in Baculovirus expression system using poly (Glu-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466392(CHEMBL4285448)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant His-tagged human Axl (473 to end residues) cytoplasmic domain expressed in insect system using poly (Glu-Ala-Tyr) peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466392(CHEMBL4285448)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant GST-tagged human Mer (578 to 872 residues) cytoplasmic domain expressed in Baculovirus system using poly (Glu-Ala-Tyr) pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed