BDBM50466741 CHEMBL4291768

SMILES CSc1cc(C)nc(SC)c1NC(=O)CN1CCN(CCSc2nc3ncccc3o2)CC1

InChI Key InChIKey=XYHAZQCTATWYDN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50466741   

TargetSterol O-acyltransferase 1(Human)
Kowa

Curated by ChEMBL
LigandPNGBDBM50466741(CHEMBL4291768)
Affinity DataIC50: 100nMAssay Description:Inhibition of ACAT in human J774A.1 cells assessed as reduction in esterified-cholesterol accumulation after 18 hrs in presence of 25-hydroxycholeste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed