BDBM50466966 CHEMBL4290861

SMILES CN(C)[C@H]1CCCC[C@@H]1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1

InChI Key InChIKey=RTLDPKPAUBOXGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466966   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM50466966(CHEMBL4290861)
Affinity DataIC50: 38.2nMAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM50466966(CHEMBL4290861)
Affinity DataIC50: 38nMAssay Description:Binding affinity to recombinant human Nav1.7 after 18 hrs by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed