BDBM50467012 CHEMBL4286456

SMILES CNC(=O)Nc1sc2c(cc(NS(=O)(=O)c3cccc(C)c3)cc2c1C(N)=O)C(C)C

InChI Key InChIKey=IRGAVEDIAARWCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50467012   

TargetAurora kinase B(Human)
Mta-Se Pathobiochemistry Research Group

Curated by ChEMBL
LigandPNGBDBM50467012(CHEMBL4286456)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant Aurora B (unknown origin) using TAMRA-PKAtide as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Mta-Se Pathobiochemistry Research Group

Curated by ChEMBL
LigandPNGBDBM50467012(CHEMBL4286456)
Affinity DataIC50: 95nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) using TAMRA-PKAtide as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed