BDBM50467110 CHEMBL4278200

SMILES CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@H]1Cc2c[n+](CCCCCCNC(=O)[C@@H](NC(=O)[C@H](CO)NC1=O)[C@@H](C)OP(O)(O)=O)cn2CCCCCCCCc1ccccc1

InChI Key InChIKey=KPDOBADQSPMGFP-UHFFFAOYSA-O

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50467110   

TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467110(CHEMBL4278200)
Affinity DataIC50: 44nMAssay Description:Inhibition of full-length myc-tagged Plk1 C-terminal polo-box domain (unknown origin) assessed as inhibition of Plk1-Biotin-Ahx-PMQS(pT)PLN-NH2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467110(CHEMBL4278200)
Affinity DataIC50: 80nMAssay Description:Inhibition of 5CF-PLATSpTPKNG-NH2 binding to Plk3 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467110(CHEMBL4278200)
Affinity DataIC50: 110nMAssay Description:Inhibition of 5CF-GPMQTSpTPKNG-NH2 binding to Plk2 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50467110(CHEMBL4278200)
Affinity DataIC50: 5nMAssay Description:Inhibition of 5CF-GPMQSpTPLNG-NH2 binding to Plk1 C-terminal polo-box domain (unknown origin) preincubated for 30 mins followed by probe addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed