BDBM50467413 CHEMBL4290748

SMILES CC(=O)Nc1ccc(cc1)-c1ccnc(Nc2ccc(OCCCCCC(=O)NO)cc2)n1

InChI Key InChIKey=MAVWGMQNCQUOBZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467413   

TargetHistone deacetylase 6(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50467413(CHEMBL4290748)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50467413(CHEMBL4290748)
Affinity DataIC50: 33nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50467413(CHEMBL4290748)
Affinity DataIC50: 89nMAssay Description:Inhibition of HDAC1 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed