BDBM50467418 CHEMBL4290297

SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2ccc(NC(C)=O)cc2)cc1

InChI Key InChIKey=DNKLFZQOGLHBPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467418   

TargetTyrosine-protein kinase JAK2(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50467418(CHEMBL4290297)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed