BDBM50467754 CHEMBL4286399

SMILES COc1cc(C)c(Cc2cc3CN(CCc3s2)C#N)cc1[C@@H]1O[C@H](CO)[C@@H](F)[C@H](O)[C@H]1O

InChI Key InChIKey=MNCHCPLVIYRKIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50467754   

TargetSodium/glucose cotransporter 2(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50467754(CHEMBL4286399)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50467754(CHEMBL4286399)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed