BDBM50467983 CHEMBL4286477

SMILES CC(C)(C)S(=O)(=O)c1ccc2nccc(Nc3n[nH]c4CCCCc34)c2c1

InChI Key InChIKey=ICFHBKASGMSAQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467983   

LigandPNGBDBM50467983(CHEMBL4286477)
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50467983(CHEMBL4286477)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50467983(CHEMBL4286477)
Affinity DataIC50: 8.64E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by Qpatch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed