BDBM50468126 CHEMBL4280531

SMILES CCOc1cc(CN2CCC3(CC2)CCN(CC3)S(=O)(=O)c2cccnc2)cc(OCC)c1-c1ccc(F)cc1

InChI Key InChIKey=CDOLWFQFQZOXNZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468126   

TargetSomatostatin receptor type 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50468126(CHEMBL4280531)
Affinity DataIC50: 13nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50468126(CHEMBL4280531)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50468126(CHEMBL4280531)
Affinity DataIC50: 210nMAssay Description:Inhibition of MK-499 binding to human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed