BDBM50468140 CHEMBL4288334

SMILES Cc1cc(c(CN2CCC3(CN(C(=O)O3)c3ccc(cc3)C(O)=O)CC2)cc1C(F)(F)F)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=NSTBZGRGMVTWSK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468140   

TargetSomatostatin receptor type 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50468140(CHEMBL4288334)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50468140(CHEMBL4288334)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50468140(CHEMBL4288334)
Affinity DataIC50: 174nMAssay Description:Antagonist activity at mouse SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed