BDBM50468610 CHEMBL4292534

SMILES Cc1ccc(N2CCN(CC2)c2ccc(\C=N\NC(=O)c3ccc(cc3)S(N)(=O)=O)cc2)c(C)c1

InChI Key InChIKey=BVPOYMRJRPTEGB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50468610   

TargetCarbonic anhydrase 7(Human)
University of Delhi

Curated by ChEMBL
LigandPNGBDBM50468610(CHEMBL4292534)
Affinity DataKi:  18nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 assessed as CO2 hydration preincubated for 15 mins prior to testing measured for 10 to 100 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Delhi

Curated by ChEMBL
LigandPNGBDBM50468610(CHEMBL4292534)
Affinity DataKi:  1.66E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 assessed as CO2 hydration preincubated for 15 mins prior to testing measured for 10 to 100 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Delhi

Curated by ChEMBL
LigandPNGBDBM50468610(CHEMBL4292534)
Affinity DataKi:  9.39E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 assessed as CO2 hydration preincubated for 15 mins prior to testing measured for 10 to 100 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Delhi

Curated by ChEMBL
LigandPNGBDBM50468610(CHEMBL4292534)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 assessed as CO2 hydration preincubated for 15 mins prior to testing measured for 10 to 100 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed