BDBM50468660 CHEMBL4283989

SMILES CCOC(=O)c1c(Cc2c(Cl)cccc2Cl)[nH]c2c1cc(O)c1ccccc21

InChI Key InChIKey=SHQLRTMVQNULDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50468660   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Campania Luigi Vanvitelli

Curated by ChEMBL
LigandPNGBDBM50468660(CHEMBL4283989)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Campania Luigi Vanvitelli

Curated by ChEMBL
LigandPNGBDBM50468660(CHEMBL4283989)
Affinity DataIC50: 782nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed