BDBM50468680 CHEMBL4291296

SMILES Oc1ccc2oc(cc(=O)c2c1)C(=O)NCCC1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=QSZSCUZHHCRPOC-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50468680   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50468680(CHEMBL4291296)
Affinity DataKi:  42nMAssay Description:Displacement of (+)-[3H]pentazocine from guinea pig brain membrane sigma1 receptor by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50468680(CHEMBL4291296)
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50468680(CHEMBL4291296)
Affinity DataKi:  345nMAssay Description:Displacement of [3H]DTG from sigma2 receptor in rat liver membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50468680(CHEMBL4291296)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine as substrate pretreated for 5 mins followed by substrate addition and measured for 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50468680(CHEMBL4291296)
Affinity DataIC50: 3.93E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using p-tyramine as substrate pretreated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50468680(CHEMBL4291296)
Affinity DataIC50: 5.12E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using p-tyramine as substrate pretreated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50468680(CHEMBL4291296)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 5-lipoxygenase using arachidonic acid as substrate pretreated for 10 mins followed by substrate and ATP addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed