BDBM50468686 CHEMBL4294609

SMILES Oc1ccc2[nH]c(cc(=O)c2c1)C(=O)NCCC1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=NWLCFCJTFBZULK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50468686   

TargetAcetylcholinesterase(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50468686(CHEMBL4294609)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50468686(CHEMBL4294609)
Affinity DataIC50: 9.88E+3nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine as substrate pretreated for 5 mins followed by substrate addition and measured for 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50468686(CHEMBL4294609)
Affinity DataIC50: 5.13E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using p-tyramine as substrate pretreated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
IQM-CSIC

Curated by ChEMBL
LigandPNGBDBM50468686(CHEMBL4294609)
Affinity DataIC50: 5.99E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using p-tyramine as substrate pretreated for 15 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed