BDBM50468781 CHEMBL4285791

SMILES COc1ccc(cc1)-c1ccc(Sc2cc(=O)n(O)c(=O)[nH]2)cc1

InChI Key InChIKey=YLHZCZYVZCUNFO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50468781   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468781(CHEMBL4285791)
Affinity DataIC50: 6nMAssay Description:Inhibition of HIV1 reverse transcriptase RNaseH activity using 3'-fluorescein/5'-Dabcyl labeled HTS-1 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468781(CHEMBL4285791)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV integrase strand transfer activity using 5'-biotin/3'-Cy5-labeled DNA substrate preincubated for 5 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468781(CHEMBL4285791)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HIV1 reverse transcriptase polymerase activity using 18 nucleotide DNA primer and 100 nucleotide DNA template after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTripartite terminase subunit 3(HHV-5)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50468781(CHEMBL4285791)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human cytomegalovirus pUL89 endonuclease activity using 60 bp dsDNA substrate incubated for 30 mins by ELISA-based biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed