BDBM50468902 CHEMBL4288881

SMILES CO[C@H](C)[C@@H]1N(C)C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)[C@H](C)NC(=O)C(=C)N(C)C(=O)[C@@H](Cc2ccccc2)OC(=O)[C@@H](NC(C)=O)[C@@H](C)OC1=O)[C@H](OC(=O)[C@@H](NC(C)=O)[C@H](O)C(C)C)C(C)C

InChI Key InChIKey=QVYLWCAYZGFGNF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50468902   

TargetGuanine nucleotide-binding protein subunit alpha-11(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468902(CHEMBL4288881)
Affinity DataIC50: 155nMAssay Description:Inhibition of recombinant human Gq/11 coupled N-terminal 3His-tagged M1 receptor expressed in CHOK1 cells assessed as reduction in carbachol-induced ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50468902(CHEMBL4288881)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Gs coupled adrenergic beta2 receptor in HEK293 cells assessed as reduction in isoproterenol-induced cAMP production pretreated for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGuanine nucleotide-binding protein G(o) subunit alpha(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468902(CHEMBL4288881)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant rat Gi coupled mGlu2 receptor expressed in CHO cells assessed as suppression of L-glutamate-induced decrease in cAMP level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGuanine nucleotide-binding protein subunit alpha-11(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468902(CHEMBL4288881)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human Gq/11 coupled N-terminal 3His-tagged M1 receptor expressed in CHOK1 cells assessed as reduction in carbachol-induced ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGuanine nucleotide binding protein, alpha q polypeptide(Chinese hamster)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50468902(CHEMBL4288881)
Affinity DataIC50: 95nMAssay Description:Inhibition of Gq-mediated signalling in CHOK1 cells stably expressing M1 muscarinic receptor assessed as inhibition of carbachol-induced IP1 producti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
LigandPNGBDBM50468902(CHEMBL4288881)
Affinity DataIC50: 100nMAssay Description:Inhibition of G-alphaq/11 in human platelet rich plasma assessed as inhibition of ADP-mediated platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGuanine nucleotide-binding protein G(q) subunit alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50468902(CHEMBL4288881)
Affinity DataIC50: 100nMAssay Description:Inhibition of G-alphaq/11 in human platelet rich plasma assessed as inhibition of ADP-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGuanine nucleotide-binding protein G(q) subunit alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50468902(CHEMBL4288881)
Affinity DataIC50: 100nMAssay Description:Inhibition of Galphaq/11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed