BDBM50469013 CHEMBL4277644

SMILES Cc1ccccc1CN1CCC(CCNC(=O)\C=C\c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)CC1

InChI Key InChIKey=PTGRNZYASAEVPN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469013   

TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469013(CHEMBL4277644)
Affinity DataIC50: 870nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate incubated for 5 mins followed by substrate addition measured after 180 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469013(CHEMBL4277644)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine chloride as substrate incubated for 5 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469013(CHEMBL4277644)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate incubated for 15 mins followed by substrate addition measured for 20 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469013(CHEMBL4277644)
Affinity DataIC50: 6.93E+4nMAssay Description:Inhibition of human MAO-A using p-tyramine as substrate incubated for 15 mins followed by substrate addition measured for 20 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed