BDBM50469122 CHEMBL4278637

SMILES [#8]-c1cccc(\[#6]=[#6]-2\c3ccccc3-[#6](=O)-c3ccccc-23)c1

InChI Key InChIKey=QDVHILRKGSWOJR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469122   

TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469122(CHEMBL4278637)
Affinity DataIC50: 316nMAssay Description:Inhibition of R1881-induced full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct after 72 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469122(CHEMBL4278637)
Affinity DataIC50: 350nMAssay Description:Inhibition of full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct assessed as reduction in R1881-induced secr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469122(CHEMBL4278637)
Affinity DataIC50: 625nMAssay Description:Displacement of Fluormone-DHT from rat GST-tagged rat AR LBD expressed in insect cells after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Vancouver Prostate Centre (Vpc)

Curated by ChEMBL
LigandPNGBDBM50469122(CHEMBL4278637)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of R1881-induced transcriptional activity of human AR V7 truncated mutant expressed in human PC3 cells harboring pGL3-ARR3tk-NLuc after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed