BDBM50469219 CHEMBL4282762

SMILES COc1cc(\C=C\C(=O)c2ccc(OCC(=O)Nc3ccc4C(=O)OCc4c3)cc2)cc(OC)c1OC

InChI Key InChIKey=QFXARAACOLICAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50469219   

TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management

Curated by ChEMBL
LigandPNGBDBM50469219(CHEMBL4282762)
Affinity DataIC50: 7.38E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate in presence of NAD+ after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Rheinische Friedrich-Wilhelms-University of Bonn

Curated by ChEMBL
LigandPNGBDBM50469219(CHEMBL4282762)
Affinity DataIC50: 8.44E+3nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in MDCK II BCRP cells assessed as effect on pheophorbide A accumulation after 120 mins by flow cytomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed