BDBM50469229 CHEMBL4277887

SMILES Nc1nc2oc3ccc(cc3c(=O)c2cc1C(=O)Nc1nn[nH]n1)N1CCOCC1

InChI Key InChIKey=AJNUNEZPUCBMIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50469229   

TargetSerine/threonine-protein kinase TBK1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50469229(CHEMBL4277887)
Affinity DataIC50: 760nMAssay Description:Inhibition of human TBK1 (1 to 657 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50469229(CHEMBL4277887)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human IKKepsilon (1 to 655 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed