BDBM50469236 CHEMBL4284757

SMILES Nc1nc2oc3ccc(cc3c(=O)c2cc1-c1nn[nH]n1)C1CCCCC1

InChI Key InChIKey=RSOFTPCUQSPDOD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469236   

TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50469236(CHEMBL4284757)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human IKKepsilon (1 to 655 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50469236(CHEMBL4284757)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human IKKepsilon (1 to 655 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50469236(CHEMBL4284757)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human TBK1 (1 to 657 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50469236(CHEMBL4284757)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of human TBK1 (1 to 657 residues) expressed in Baculovirus infected SF9 insect cells using myelin basic protein as substrate in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed