BDBM50469252 CHEMBL4287122

SMILES [H][C@@]12C[C@@]3([H])C[C@@](CNc4nc(NCc5ccccc5C(F)(F)F)ncc4C#N)(C1)C[C@@]([H])(C2)[C@H]3N

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50469252   

TargetProtein kinase C theta type(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50469252(CHEMBL4287122)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant full-length human PKCtheta using STK1-biotin as substrate preincubated for 60 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed