BDBM50469364 CHEMBL4291006

SMILES CCCCNc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(NC2CCNCC2)cc1

InChI Key InChIKey=ZFBBKOBKYNRTOS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469364   

TargetTyrosine-protein kinase receptor UFO(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469364(CHEMBL4291006)
Affinity DataIC50: 42nMAssay Description:Inhibition of AXL (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469364(CHEMBL4291006)
Affinity DataIC50: 34nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469364(CHEMBL4291006)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469364(CHEMBL4291006)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of FLT3 (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed