BDBM50469367 CHEMBL4294601

SMILES CCC[C@H](C)Nc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(CN2CC[C@@H](C2)N(C)C)cc1

InChI Key InChIKey=JLSYAJGCSIAVIW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469367   

TargetTyrosine-protein kinase Mer(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469367(CHEMBL4294601)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469367(CHEMBL4294601)
Affinity DataIC50: 11nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469367(CHEMBL4294601)
Affinity DataIC50: 51nMAssay Description:Inhibition of FLT3 (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469367(CHEMBL4294601)
Affinity DataIC50: 152nMAssay Description:Inhibition of AXL (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed