BDBM50469368 CHEMBL4284392

SMILES CCC[C@H](C)Nc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(cc1F)S(=O)(=O)N1CCN(C)CC1

InChI Key InChIKey=YAXKZYIBIZYKIR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469368   

TargetTyrosine-protein kinase Mer(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469368(CHEMBL4284392)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469368(CHEMBL4284392)
Affinity DataIC50: 33nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469368(CHEMBL4284392)
Affinity DataIC50: 189nMAssay Description:Inhibition of FLT3 (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469368(CHEMBL4284392)
Affinity DataIC50: 191nMAssay Description:Inhibition of AXL (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed