BDBM50469524 CHEMBL4283548

SMILES Fc1ccc2c(noc2c1)C1CCN(CCCCc2cc3CCN4c3c(CCC4=O)c2)CC1

InChI Key InChIKey=UIXQJBAAWGMZKH-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50469524   

TargetD(2) dopamine receptor(Rat)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50469524(CHEMBL4283548)
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor in rat striatum homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50469524(CHEMBL4283548)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-8-OH-DPAT from serotonin 5-HT1A receptor in rat brain cortex homogenates incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50469524(CHEMBL4283548)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-lysergic acid diethylamide from human serotonin 5-HT6 receptor expressed in CHO cell membranes incubated for 30 mins by liquid s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50469524(CHEMBL4283548)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-ketanserine from serotonin 5-HT2A receptor in rat brain cortex homogenates incubated for 30 mins by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50469524(CHEMBL4283548)
Affinity DataKi:  55nMAssay Description:Displacement of [3H] 7-OH-DPAT from dopamine D3 receptor in rat olfactory tubercle homogenates after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50469524(CHEMBL4283548)
Affinity DataKi:  99nMAssay Description:Displacement of [3H]-prazosin from alpha-1 adrenergic receptor in rat cerebral cortex homogenates incubated for 60 mins by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50469524(CHEMBL4283548)
Affinity DataKi:  540nMAssay Description:Displacement of [3H]-mesulergine from serotonin 5-HT2C receptor in rat brain cerebral cortex homogenates incubated for 15 mins by liquid scintillatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50469524(CHEMBL4283548)
Affinity DataKi:  712nMAssay Description:Displacement of [3H]-mepyramine from histamine H1 receptor in guinea pig cerebellum homogenates incubated for 60 mins by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed