BDBM50470457 CHEMBL4292571

SMILES CNc1ncc(C(=O)OCc2cccc(F)c2)c2nc(nn12)-c1ccco1

InChI Key InChIKey=NWWKYDWORDCFBN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50470457   

TargetAdenosine receptor A3(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50470457(CHEMBL4292571)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]HEMADO from human adenosine A3 receptor expressed in CHO cell membranes after 3 hrs by micro beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50470457(CHEMBL4292571)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cell membranes after 3 hrs by micro beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50470457(CHEMBL4292571)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cell membranes after 3 hrs by micro beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Trieste

Curated by ChEMBL
LigandPNGBDBM50470457(CHEMBL4292571)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cell membranes assessed as inhibition of NECA-stimulated adenylyl cyclase activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed