BDBM50470562 CHEMBL1230055

SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(Cl)c3)ncnc12)C(O)=O

InChI Key InChIKey=VGYBDYWAAOWMTJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50470562   

TargetGenome polyprotein(Dengue virus)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50470562(CHEMBL1230055)
Affinity DataKi:  170nMAssay Description:Inhibition of N-terminal GST tagged recombinant Dengue virus 3 2'-O methyltransferase expressed in Escherichia coli BL21 cells by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50470562(CHEMBL1230055)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human DNMT1A using double-stranded hemi-DNA oligonucleotide as substrate measured after 40 mins by [3H]methyl incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50470562(CHEMBL1230055)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged RNMT (1 to 476 residues) expressed in Escherichia coli BL21 using 5'-GpppAGAACCUG-biotin-TEG-3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed