BDBM50471114 CHEMBL61418

SMILES COc1ccc2[nH]cc3CC(Cc1c23)NC(C)=O

InChI Key InChIKey=PXAVOXIFTCTBHZ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50471114   

TargetMelatonin receptor type 1A/1B(Human)
University of Urbino

Curated by ChEMBL
LigandPNGBDBM50471114(CHEMBL61418)
Affinity DataKi:  330nMAssay Description:Binding affinity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as labelled ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
University of Urbino

Curated by ChEMBL
LigandPNGBDBM50471114(CHEMBL61418)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against melatonin receptor in the quail optica tecta using 2-[125] iodomelatonin as radiolabeled ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
University of Urbino

Curated by ChEMBL
LigandPNGBDBM50471114(CHEMBL61418)
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibitory activity against melatonin receptor of quail optica tecta with 200 pM 2-[125] iodomelatoninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1A/1B(Human)
University of Urbino

Curated by ChEMBL
LigandPNGBDBM50471114(CHEMBL61418)
Affinity DataIC50: 8.97E+3nMAssay Description:Inhibitory activity against melatonin receptor of quail optica tecta with 200 pM 2-[125] iodomelatonin as gamma-S (10e-4 M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed