BDBM50473107 CHEMBL341700

SMILES C1Nc2cc[n+](Cc3cccc(C[n+]4ccc(NCc5cccc1c5)c1ccccc41)c3)c1ccccc21

InChI Key InChIKey=MLPCLFHDLFQJCN-UHFFFAOYSA-P

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50473107   

TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rat)
Aristotelian University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50473107(CHEMBL341700)
Affinity DataIC50: 130nMAssay Description:Inhibition of after hyperpolarization (AHP) of cultured rat sympathetic neurons as SKCa channel blocking activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rat)
Aristotelian University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50473107(CHEMBL341700)
Affinity DataIC50: 130nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed