BDBM50473345 CHEMBL316413

SMILES COc1ccc(cc1OC)C1=NNC(=O)C(C)C1C

InChI Key InChIKey=MDGJFJLCWGQWRG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50473345   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50473345(CHEMBL316413)
Affinity DataIC50: 630nMAssay Description:Inhibition of PDE4 in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50473345(CHEMBL316413)
Affinity DataIC50: 631nMAssay Description:Inhibition of PDE4 in the cytosol of human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50473345(CHEMBL316413)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of PDE3 in homogenates of human blood plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50473345(CHEMBL316413)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE3 in homogenates of human blood plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed