BDBM50473776 CHEMBL358814

SMILES C[S+]([O-])c1ccccc1CSc1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1

InChI Key InChIKey=KRRCAAGRJZQAMA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50473776   

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50473776(CHEMBL358814)
Affinity DataIC50: 900nMAssay Description:Inhibition of p38 MAP kinase related interleukin (IL1-beta (cytokine) release from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50473776(CHEMBL358814)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of p38 MAP kinase related interleukin (IL1-beta (cytokine) release from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50473776(CHEMBL358814)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of p38 MAP kinase related TNF-alpha release from peripheral blood mononuclear cells (PBMC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50473776(CHEMBL358814)
Affinity DataIC50: 4.75E+4nMAssay Description:Inhibition of p38 MAP kinase related TNF-alpha release from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed