BDBM50473777 CHEMBL93079

SMILES C[S+]([O-])c1cccc(CSc2ncc(-c3ccc(F)cc3)c(n2)-c2ccncc2)c1

InChI Key InChIKey=LMTKLNLLCGIZBN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50473777   

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50473777(CHEMBL93079)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of p38 MAP kinase related interleukin (IL1-beta (cytokine) release from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50473777(CHEMBL93079)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of p38 MAP kinase related TNF-alpha release from peripheral blood mononuclear cells (PBMC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50473777(CHEMBL93079)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed