BDBM50474433 CHEMBL440730

SMILES [H][C@]1(Cc2c[nH]cn2)CCNC1

InChI Key InChIKey=YGGBVTGACIFVRB-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50474433   

TargetHistamine H3 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474433(CHEMBL440730)
Affinity DataEC50:  2.10nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474433(CHEMBL440730)
Affinity DataKi:  5.20nMAssay Description:Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474433(CHEMBL440730)
Affinity DataKi:  37.2nMAssay Description:Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50474433(CHEMBL440730)
Affinity DataEC50:  417nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed