BDBM50474886 CHEMBL182342

SMILES OC(CCN1CCCCC1)c1ccc(cc1)-c1c2c(cc3ccc(O)cc13)sc1cc(O)ccc21

InChI Key InChIKey=VGFUTXNYAMRULN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50474886   

TargetEstrogen receptor beta(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50474886(CHEMBL182342)
Affinity DataIC50: 1nMAssay Description:Antagonist effect against 10 pM 17-beta-estradiol induced MCF-7 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50474886(CHEMBL182342)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity as alkaline phosphatase induction in Ishikawa endometrial cells compared to E2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50474886(CHEMBL182342)
Affinity DataIC50: 690nMAssay Description:Antagonist activity as inhibition of 1 nM 17-beta-estradiol stimulated alkaline phosphatase induction in Ishikawa endometrial cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed