BDBM50476460 CHEMBL232292

SMILES Fc1ccc2CCC(COC(=O)NCCCn3ccnc3)N(c2c1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=YYDLJWLXGUNJPL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50476460   

TargetPresenilin-1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50476460(CHEMBL232292)
Affinity DataIC50: 270nMAssay Description:Inhibition of gamma secretase-mediated amyloid-beta peptid aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed