BDBM50476539 CHEMBL437708

SMILES Oc1nc(nc(C(=O)NCc2ccccc2)c1O)-c1cccs1

InChI Key InChIKey=HGXMRTJYNJENOK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50476539   

TargetIntegrase(Human immunodeficiency virus type 1)
Irbm-Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50476539(CHEMBL437708)
Affinity DataIC50: 85nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Irbm-Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50476539(CHEMBL437708)
Affinity DataIC50: 85nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetTripartite terminase subunit 3(HHV-5)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50476539(CHEMBL437708)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human cytomegalovirus pHAR-UL89C expressed in Escherichia coli Rosette using Digoxigenin-labeled 5'-taatcgccttgcagcacatccccattcgccagctg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50476539(CHEMBL437708)
Affinity DataIC50: 85nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50476539(CHEMBL437708)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of HIV-1 integrase G140S/Q148K double mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed