BDBM50476802 CHEMBL395568

SMILES COc1cc2cc[n+](C)c(Cc3ccccc3Cc3[n+](C)ccc4cc(OC)c(OC)c(OC)c34)c2c(OC)c1OC

InChI Key InChIKey=ROTPHKOTMHELTA-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50476802   

TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rat)
University of Li£Ge

Curated by ChEMBL

LigandBDBM50476802(CHEMBL395568)Copy SMILESCopy InChI

Affinity DataIC50: 4.10E+3nMAssay Description:Blockade of SK channel in Wistar rat brain assessed as inhibition of apamin-sensitive after-hyperpolarisationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/24/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetSmall conductance calcium-activated potassium channel protein 1/2/3(Rat)
University of Li£Ge

Curated by ChEMBL

LigandBDBM50476802(CHEMBL395568)Copy SMILESCopy InChI

Affinity DataKi:  35nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/24/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL