BDBM50476837 CHEMBL234237

SMILES Cn1cc(C(O)=O)c(Nc2ccc(I)cc2F)cc1=O

InChI Key InChIKey=DSKCFNMBWKCOQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50476837   

TargetDual specificity mitogen-activated protein kinase kinase 1/2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50476837(CHEMBL234237)
Affinity DataIC50: 425nMAssay Description:Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50476837(CHEMBL234237)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MEK in mouse colon 26 carcinoma cells assessed as inhibition of ERK phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed