BDBM50477510 CHEMBL246370

SMILES C[C@H](NC(=O)Cc1ccc(F)cc1)C(=O)NC1c2ccccc2C=NN(C)C1=O

InChI Key InChIKey=YRNULWHSWZKWLM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477510   

TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50477510(CHEMBL246370)
Affinity DataIC50: 59nMAssay Description:Inhibition of gamma secretase assessed as reduction of amyloid beta level in H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed