BDBM50477534 CHEMBL397394

SMILES CC(C)C[C@H](NC(=O)Cc1cccs1)C(=O)NC1c2ccccc2C=NN(C)C1=O

InChI Key InChIKey=FQJSJLGCMZSZQJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477534   

TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50477534(CHEMBL397394)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of gamma secretase assessed as reduction of amyloid beta level in H4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed