BDBM50478428 spongiacidin D

SMILES Brc1cc2c([nH]1)C(=O)NCC\C2=C1\NC(=O)NC1=O

InChI Key InChIKey=LEWMERXWKZWRBX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50478428   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50478428(spongiacidin D)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) in presence of gamma32P-ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50478428(spongiacidin D)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of CK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50478428(spongiacidin D)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50478428(spongiacidin D)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Protein kinase C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50478428(spongiacidin D)
Affinity DataIC50: 1.53E+5nMAssay Description:Inhibition of c-erbB-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50478428(spongiacidin D)
Affinity DataIC50: 1.53E+5nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed