BDBM50481051 CHEMBL572036

SMILES Cc1nc2-c3n[nH]cc3C(C3CC3)N(c2s1)S(=O)(=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=SFJIFYRXCCUSGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50481051   

TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50481051(CHEMBL572036)
Affinity DataIC50: 24nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed