BDBM50481410 CHEMBL597979::ZINC 02911543

SMILES OS(=O)(=O)c1cccc(NNc2ccc(Nc3ccccc3)cc2)c1

InChI Key InChIKey=QGEDDOSZYQFMIT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50481410   

TargetGenome polyprotein(DENV-2)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50481410(ZINC 02911543 | CHEMBL597979)
Affinity DataIC50: 7.56E+3nMAssay Description:Inhibition of Dengue virus type 2 NS5 RNA methyltransferase RNA siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50481410(ZINC 02911543 | CHEMBL597979)
Affinity DataIC50: 7.14E+3nMAssay Description:Inhibition of Dengue virus type 2 NS5 RNA methyltransferase RNA site with 0.1 % TX100More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50481410(ZINC 02911543 | CHEMBL597979)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of Dengue virus type 2 NS5 RNA methyltransferase by spin-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50481410(ZINC 02911543 | CHEMBL597979)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of Dengue virus type 2 NS5 RNA methyltransferase at 80 nM enzyme concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50481410(ZINC 02911543 | CHEMBL597979)
Affinity DataIC50: 7.62E+3nMAssay Description:Inhibition of Dengue virus type 2 NS5 RNA methyltransferase at 8 nM enzyme concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed