BDBM50481446 CHEMBL5267814

SMILES Cn1ncc2c(Oc3ccc(NC(=O)Nc4ccc(Cl)c(c4)C(F)(F)F)cc3)ncnc12

InChI Key InChIKey=GTYIHPYAKKJHRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481446   

TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50481446(CHEMBL5267814)
Affinity DataIC50: 24nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50481446(CHEMBL5267814)
Affinity DataIC50: 52nMAssay Description:Inhibition of wild type B-Raf (unknown origin) by Z-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed